GAPDH anticorps (AA 1-335)

N° du produit ABIN3020538

L’anticorps Lapin Polyclonal anti-GAPDH a été validé pour WB, IHC, IF et IP. Il convient pour détecter GAPDH dans des échantillons de Humain. Il y a 13+ publications disponibles.

Aperçu rapide pour GAPDH anticorps (AA 1-335) (ABIN3020538)

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAPDH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-GAPDH anticorps

Épitope: AA 1-335

Séquence: MGKVKVGVNG FGRIGRLVTR AAFNSGKVDI VAINDPFIDL NYMVYMFQYD STHGKFHGTV KAENGKLVIN GNPITIFQER DPSKIKWGDA GAEYVVESTG VFTTMEKAGA HLQGGAKRVI ISAPSADAPM FVMGVNHEKY DNSLKIISNA SCTTNCLAPL AKVIHDNFGI VEGLMTTVHA ITATQKTVDG PSGKLWRDGR GALQNIIPAS TGAAKAVGKV IPELNGKLTG MAFRVPTANV SVVDLTCRLE KPAKYDDIKK VVKQASEGPL KGILGYTEHQ VVSSDFNSDT HSSTFDAGAG IALNDHFVKL ISWYDNEFGY SNRVVDLMAH MASKE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Loading control Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human GAPDH (NP_002037.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:10000,IHC,1:50 - 1:100,IF,1:20 - 1:50,IP,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-GAPDH (ABIN3020538)

Li, Luo, Wang, Liu, Chen, Zhao, Tan, Wang, Qin, Li, Xu, Yang: "The REN4 rheostat dynamically coordinates the apical and lateral domains of Arabidopsis pollen tubes." dans: Nature communications, Vol. 9, Issue 1, pp. 2573, (2018) (PubMed).

Guo, Song, Zhao, Qi, Zhao: "Overexpression of Annexin A2 Receptor Inhibits Neovascularization via the Promotion of Krüppel-Like Transcription Factor 2." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 4, pp. 1617-1627, (2018) (PubMed).

Xue, Zhang, Wang, Zhang, Xiang, Wang, Wang, Li, Zhang, Zou, Wang, Wu, Lu, Chen, Ding, Li, Xu: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." dans: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).

Zhou, Liu, Wang, Huang, Li, Zhu, Wang, Ma, Li, Wei, Li, Li, Li, Xiao, Zhao: "Paeoniflorin attenuates ANIT-induced cholestasis by inhibiting apoptosis in vivo via mitochondria-dependent pathway." dans: Biomedicine & pharmacotherapy, Vol. 89, pp. 696-704, (2018) (PubMed).

Cui, Zhang, Liu, Yan, Huang, Yang, Zhu, Sang: "Inhibition of TBK1 reduces choroidal neovascularization in vitro and in vivo." dans: Biochemical and biophysical research communications, Vol. 503, Issue 1, pp. 202-208, (2018) (PubMed).

"Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang." dans: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 8, pp. 885, (2018) (PubMed).

Ding, Wen: "Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis." dans: Journal of natural medicines, Vol. 72, Issue 4, pp. 857-866, (2018) (PubMed).

Luo, Cai, Luo, Tang, Meng: "Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells." dans: Molecular medicine reports, Vol. 17, Issue 6, pp. 8053-8060, (2018) (PubMed).

Zhu, Ye, Ashraf, Li, Chen, Song, Cao: "Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection." dans: Scientific reports, Vol. 6, pp. 22581, (2017) (PubMed).

Wu, Jiang, Gong, Dou, Song, Song, Tian: "Vitamin E Reversed Apoptosis of Cardiomyocytes Induced by Exposure to High Dose Formaldehyde During Mice Pregnancy." dans: International heart journal, Vol. 58, Issue 5, pp. 769-777, (2017) (PubMed).

Ma, Zhang, Wang, Li, Wei, Zhao, Jin, Li, Jin: "Tanshinones suppress AURKA through up-regulation of miR-32 expression in non-small cell lung cancer." dans: Oncotarget, Vol. 6, Issue 24, pp. 20111-20, (2016) (PubMed).

Wang, Tian, Yong, Zhu, Lin, Jiang, Li, Huang, Lin: "Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice." dans: Journal of nanobiotechnology, Vol. 14, pp. 10, (2016) (PubMed).

Wu, Luo, Jiang, Wang, Wang, Wang, Fu, Li, Shi: "Marine bromophenol bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane inhibits the proliferation, migration, and invasion of hepatocellular carcinoma cells via modulating β1-integrin/FAK signaling." dans: Marine drugs, Vol. 13, Issue 2, pp. 1010-25, (2016) (PubMed).

Détails sur GAPDH

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Autre désignation: GAPDH

Sujet: This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.,G3PD,GAPD,HEL-S-162eP,GAPDH,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,GAPDH

Poids moléculaire: 31 kDa/36 kDa

ID gène: 2597

UniProt: P04406